Effects of Nutritional Support on Postoperative Delirium
Recruiting
N/AInterventional Study
Postoperative Delirium
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
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At a Glance
Age
65 and older
Sex
Any
Study type
Interventional
Purpose
Other
Participants needed
314 (estimated)
Sponsor
Yonsei University · Other
Who this trial is looking for
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This study is a prospective, single-center, randomized controlled trial to compare whether applying nutritional supplementation therapy before and after surgery in elderly patients aged 65 years or older undergoing non-cardiac surgery can reduce the incidence of postoperative delirium.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Elderly patients aged 65 and above.
* Patients undergoing non-cardiac major surgery in thoracic surgery, lung cancer surgery, multi-level spinal surgery in neurosurgery and orthopedics, or liver cancer surgery in hepatobiliary and pancreatic surgery, under general anesthesia w…
Inclusion Criteria:
* Elderly patients aged 65 and above.
* Patients undergoing non-cardiac major surgery in thoracic surgery, lung cancer surgery, multi-level spinal surgery in neurosurgery and orthopedics, or liver cancer surgery in hepatobiliary and pancreatic surgery, under general anesthesia with an expected surgery duration of 2 hours or more.
* Patients scheduled for arterial catheterization.
* Patients who are able to take oral intake from postoperative day #1.
Exclusion Criteria:
* Patients with uncontrolled systemic conditions such as diabetes, hypertension, renal disease, liver disease, and other systemic illnesses.
* Those with visual impairment.
* Patients with cognitive impairment based on the Mini-Mental State Examination for Dementia Screening criteria.
* Individuals experiencing difficulty in communication.
* Those diagnosed with neurological disorders (such as brain hemorrhage, stroke, brain tumor, dementia, Parkinson's disease, cognitive impairment, depression, etc.).
* Patients diagnosed with alcohol or substance addiction.
* Patients with cancelled scheduled surgeries.
* Patients undergoing minor surgeries with expected anesthesia durations of less than 2 hours.
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