Sensitivity of Organoids to Predict Treatment Outcome in Breast Cancer Metastases
Recruiting
Observational Study
Breast Neoplasms
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Study type
- Observational
- Participants needed
- 20 (estimated)
- Sponsor
- King's College London · Other
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About This Trial
The aim of the study is to generate patient-derived organoids (PDOs) from brain resection or biopsied extra-cranial metastases. The preliminary data collected will be used to assess the ability of PDOs to predict patients' treatment response and their radio-sensitivity and chemo-sensitivity can be correlated with their survival outcome.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Breast cancer patients with brain metastases who are suitable for surgical resection or Breast cancer patients with extra-cranial metastases undergoing surgical resection or biopsy
* Age \> 18 years old
Exclusion Criteria:
* Patients unable to give informed consent e.g., men…
Contacts