Evolution of the Initial Distribution Volume of Glucose in the Severe Burned Adults
Recruiting
Phase 2Interventional Study
BurnsIntensive CareEmergencies
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Prior Safety Data
This treatment has already been tested in at least one earlier human trial.
Ready to participate?
Review the details below, then apply to join this clinical trial.
At a Glance
Age
18 and older
Sex
Any
Trial phase
Phase 2
Study type
Interventional
Purpose
Treatment
Participants needed
15 (estimated)
Sponsor
Centre Hospitalier Régional Metz-Thionville · Other
Who this trial is looking for
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Answer a few quick questions to see if you may meet the eligibility requirements.
This is a prospective, observational, monocentric, phase II (exploratory) cohort study aiming to describe the evolutionary profile of the initial volume of glucose distribution (IDVG) during the first four days of management of severely burned patient.
Trial Locations
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Status
Eligibility Criteria
Inclusion Criteria:
* Patients over 18 years of age
* Patients hospitalized with burns of at least 30% of body surface area
* By a thermal mechanism
* At the CHR Metz-Thionville burn center
* managed within the 8 hours post-burn
* Patient affiliated to a social security scheme
* Written cons…
Inclusion Criteria:
* Patients over 18 years of age
* Patients hospitalized with burns of at least 30% of body surface area
* By a thermal mechanism
* At the CHR Metz-Thionville burn center
* managed within the 8 hours post-burn
* Patient affiliated to a social security scheme
* Written consent obtained from the patient (or from the trusted person, family or relatives if the patient is unable to sign/express consent) or emergency inclusion if the patient is unable to express consent and neither the trusted support person nor any member of the family or relatives is present at the time of inclusion.
Exclusion Criteria:
* Diabetic patients on insulin
* Patient with a CONTRAINDICATION to GLUCOSE 30% PROAMP, solution for injection
* Patients with pre-hospital cardiac arrest
* extra corporeal circulation patient: Extra Corporeal Membranous Oxygenation (ECMO) or Extra Corporeal Life Support (ECLS) or CRRT (Continuous Renal Replacement Therapy)
* patient without a central venous line or arterial catheter
* Patient moribund or immediately subject to therapeutic limitation
* Impossibility of trans-pulmonary thermodilution monitoring (vascular access difficulties)
* Pregnant, parturient or breast-feeding women
* Patient under guardianship, curatorship or safeguard of justice
* Cognitive impairment or language barrier
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