C-peptide for Better Blood Sugar Control in Type 1 Diabetes

Effect of C-peptide on Hypoglycemic Counterregulation

Recruiting Early Phase 1 Interventional Study
Hypoglycemia Type 1 Diabetes
Healthy Volunteers Welcome You do not need to have the condition being studied to take part.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
18 – 40
Sex
Any
Trial phase
Early Phase 1
Study type
Interventional
Purpose
Basic Science
Participants needed
38 (estimated)
Sponsor
University of Cincinnati · Other
Who this trial is looking for

This trial is looking for people with type 1 diabetes who often experience low blood sugar levels. Participants will help researchers understand how a natural protein called C-peptide might help improve blood sugar management.

Are You a Good Fit for This Trial?

You may be able to join if

  • I have a BMI less than 30.

You may not be able to join if

  • I am pregnant or breastfeeding.
  • I smoke cigarettes.
  • I have HIV or hepatitis.
  • I have cardiovascular disease.
  • I have microvascular disease.

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

Think this trial could be right for you?

Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.

Check Your Eligibility
About This Trial
Iatrogenic hypoglycemia is the most prominent barrier to the safe, effective management of blood sugar in people with type 1 diabetes due to periodic over-insulinization. During insulin-induced hypoglycemia, glucagon secretion is diminished in type 1 diabetes which, in turn, reduces hepatic glucose production and increases the depth and duration of hypoglycemic episodes. We have observed that the …
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * BMI less than 30 kg/m2 Exclusion Criteria: * pregnant or lactating women cigarette smoking presence of HIV or hepatitis presence of cardiovascular disease presence of microvascular disease
Contacts

Jason Winnick, PhD

513-558-4437

jason.winnick@uc.edu

CONTACT

Natalie Whitsett

513-558-4489

whitsenh@ucmail.uc.edu

CONTACT