Colistin Dosage Prsonalization Approach
Recruiting
Observational Study
Colistin Adverse Reaction
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 0 Days – 28 Days
- Sex
- Any
- Study type
- Observational
- Participants needed
- 100 (estimated)
- Sponsor
- Mahmoud I Mostafa · Other
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About This Trial
A few studies have evaluated higher doses or the administration or a loading dose, which is routine in adults, in pediatric patients, and reported improved colistin exposure without an increased risk of nephrotoxicity The main questions it aims to answer are What is the optimal dosing strategies of intravenous colistin for the treatment of multidrug-resistant gram-negative bacterial infections in …
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Neonates aged between (0-30 days) born before 37 weeks
* Critically ill patients with nosocomial infection with proven culture-resistant gram-negative bacteria.
* Neonates who are indicated for colistin and started colistin therapy for at least 48 hr.
Exclusion Criteria:
* S…
Contacts
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