Ketalar or Dexmedetomidine for Pain After Cholecystectomy
Effect of Ketalar or Dexmedetomidine on Increased Sensitivity to Pain Following Treatment With Remifentanil
Recruiting
N/AInterventional Study
Cholecystectomy
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
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At a Glance
Age
18 – 85
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
90 (estimated)
Sponsor
Assaf-Harofeh Medical Center · Government
Who this trial is looking for
This trial is looking for patients undergoing laparoscopic cholecystectomy under general anesthesia. Participants will help compare two treatments to see which one better prevents increased sensitivity to pain after using Remifentanil for pain relief.
Are You a Good Fit for This Trial?
You may be able to join if
I am scheduled for laparoscopic cholecystectomy surgery.
You may not be able to join if
I have a sensitivity to the anesthetic.
I have chronic pain and am in regular treatment.
I need to have urgent surgery.
I have ischemic heart disease.
I have known bradycardia.
I have a pacemaker.
I have used opiates for a long time.
I have kidney or liver function problems.
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer a few quick questions to see if you may meet the eligibility requirements.
Analgesia is one of the pillars of anesthesia. One of the common opiates for pain relief, with a short half-life, is Remifentanil. However, following Remifentanil treatment an increased sensitivity to pain \[hyperalgesia\] appears. The aim of the study is to compare the effects between complementary treatments, like Ketalar and Dexmedetomidine, in preventing increased sensitivity to pain after Rem…
Analgesia is one of the pillars of anesthesia. One of the common opiates for pain relief, with a short half-life, is Remifentanil. However, following Remifentanil treatment an increased sensitivity to pain \[hyperalgesia\] appears. The aim of the study is to compare the effects between complementary treatments, like Ketalar and Dexmedetomidine, in preventing increased sensitivity to pain after Remifentanil treatment
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
• Patients who are about to undergo alaparoscopic cholecystectomy under general anesthesia
Exclusion Criteria:
* Patients with sensitivity to the anesthetic
* Patients with chronic pain who are in regular treatment
* Urgent surgery
* Patients with ischemic heart disease
* Pati…
Inclusion Criteria:
• Patients who are about to undergo alaparoscopic cholecystectomy under general anesthesia
Exclusion Criteria:
* Patients with sensitivity to the anesthetic
* Patients with chronic pain who are in regular treatment
* Urgent surgery
* Patients with ischemic heart disease
* Patients with known bradycardia
* Patients with a pacemaker
* Prolonged use of opiates
* Kidney/liver function problems
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