Assessment of T-cell Response and In-vitro Proof-of-concept of T-cell Engineering in Chronic ESKD Patients.

Recruiting Observational Study
Chronic Kidney Diseases
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Healthy Volunteers Welcome You do not need to have the condition being studied to take part. No Study Drug Researchers observe your health over time — no experimental treatment is given.
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At a Glance
Age
18 and older
Sex
Any
Study type
Observational
Participants needed
100 (estimated)
Sponsor
Centre Hospitalier Régional d'Orléans · Other
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About This Trial
This is a comparative, prospective, non-interventional study to evaluate immune response in patients with chronic kidney disease. The primary objective is to define immunodeficiency (phenotype and function of T cells) in patients with end-stage kidney disease. The second objective is to provide an in-vitro proof-of-concept of T-cell engineering in the context of end-stage kidney disease. The stud…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: 1. Male or female ≥ 18 years 2. Informed participants who did not object to participating in the study Exclusion Criteria: 1. Chronic progressive infections 2. Prior organ transplantation (including bone marrow transplantation) 3. Previous treatment with immunosuppressive agen…
Contacts

Manon DEKEYSER, PhD

+33238229870

manon.dekeyser@chu-orleans.fr

CONTACT