Multidimensional Phenotype Classification in Grade 3 Bronchopulmonary Dysplasia

Recruiting Observational Study
Bronchopulmonary Dysplasia
No Placebo Group Every participant receives an active treatment — no one gets a placebo. No Study Drug Researchers observe your health over time — no experimental treatment is given.
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At a Glance
Age
1 Month – 1
Sex
Any
Study type
Observational
Participants needed
130 (estimated)
Sponsor
Children's Hospital of Philadelphia · Other
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About This Trial
Bronchopulmonary Dysplasia (BPD), or chronic lung disease of prematurity, is the most consequential complication of preterm birth and is strong predictor of childhood pulmonary and neurodevelopmental disability, particularly in infants diagnosed with grade 3 BPD (ventilator dependence at 36 weeks' postmenstrual age), the most severe disease form. This study aims to (1) generate the first empirical…
Trial Locations
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Eligibility Criteria
Inclusion Criteria (infant subjects): * Male or female infant born with gestational age \<32 weeks * Postmenstrual age between 36-65 weeks at enrollment * Receiving invasive ventilation at enrollment * Grade 3 BPD or grade 2 BPD with need for chronic invasive ventilation at enrollment * Parental in…
Contacts

Erik Jensen, MD, MSCE

267-648-2720

jensene@chop.edu

CONTACT

Krithika Lingappan, MD, PhD

8324058684

lingappank@chop.edu

CONTACT