No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
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Review the details below, then apply to join this clinical trial.
At a Glance
Age
45 – 70
Sex
Female
Study type
Interventional
Purpose
Other
Participants needed
5 (estimated)
Sponsor
University of California, Davis · Other
Who this trial is looking for
This trial is looking for postmenopausal women aged 45 to 70 who want to try Chardonnay Marc powder to see how it affects gut and heart health. Participants will need to follow the study guidelines during the trial.
Are You a Good Fit for This Trial?
Rules you outHigh blood pressureHeart diseaseLiver diseaseRenal diseaseCancer within the past 5 yearsGastrointestinal disordersSubstance or alcohol abuseSmoking
You may be able to join if
I am a postmenopausal female and have not had a period for at least 2 years.
I am between 45 and 70 years old.
My BMI is between 25 and 49.9.
My fasting triglycerides are above 120 mg/dL.
I am willing to follow the study protocols.
You may not be able to join if
I take daily anticoagulation medications including aspirin or NSAIDs.
I follow a vegan or vegetarian diet.
I eat more than 3 cups of fruit a day.
I eat more than 4 cups of vegetables a day.
I drink more than 3 cups of coffee or tea a day.
I consume more than 3 oz of dark chocolate a day.
I have had heart disease or a stroke.
I have a chronic health condition that limits my physical activity.
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer a few quick questions to see if you may meet the eligibility requirements.
Recently a dietary recommendation of 400 - 600 mg/ day has been proposed for the reduced risk of developing cardiovascular disease. Dietary flavanols can be obtained from the intake of foods such as tea, cocoa, wine, berries and apples. Incorporating Chardonnay Marc (the skins and seeds of Chardonnay grapes) into the diet can be an additional source of dietary flavanols. Like other flavanol-rich f…
Recently a dietary recommendation of 400 - 600 mg/ day has been proposed for the reduced risk of developing cardiovascular disease. Dietary flavanols can be obtained from the intake of foods such as tea, cocoa, wine, berries and apples. Incorporating Chardonnay Marc (the skins and seeds of Chardonnay grapes) into the diet can be an additional source of dietary flavanols. Like other flavanol-rich foods, Chardonnay Marc provides fiber and polysaccharides that may benefit gut health. This study seeks pilot data on the impact of the daily incorporation of Chardonnay Marc powder into the diet on markers of gut and cardiometabolic health.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Postmenopausal female, with a cessation of menses for at least 2 years
* 45-70 years of age
* BMI 25- 49.9 kg/m2
* Fasting triglycerides \> 120 mg/dL
* Subject is willing and able to comply with the study protocols and procedures.
Exclusion Criteria:
* Self-reported use of d…
Inclusion Criteria:
* Postmenopausal female, with a cessation of menses for at least 2 years
* 45-70 years of age
* BMI 25- 49.9 kg/m2
* Fasting triglycerides \> 120 mg/dL
* Subject is willing and able to comply with the study protocols and procedures.
Exclusion Criteria:
* Self-reported use of daily anticoagulation agents including aspirin, NSAIDs
* Prescription medications and supplements, except for a 6 month stable dose of thyroid medications
* Vegan, Vegetarians, food faddists or those consuming a non-traditional diet
* Fruit consumption ≥ 3 cups/day
* Vegetable consumption ≥ 4 cups/day
* Coffee/tea ≥ 3 cups/day
* Dark chocolate ≥ 3 oz/day
* Self-reported restriction of physical activity due to a chronic health condition
* Self-reported chronic/routine high intensity exercise
* Blood pressure ≥ 140/90 mm Hg
* Self-reported renal or liver disease
* Self-reported heart disease, which includes cardiovascular events and stroke, diabetes
* Peripheral artery disease Raynaud's syndrome or disease
* Inability to properly place or wear the PAT probes or abnormal measurements on pre-screening PAT
* Self-reported cancer within past 5 years
* Self-reported gastrointestinal disorders, apart from appendix removal
* Unwillingness to stop any supplement use, including herbal, plant or botanical, fish oil, oil supplements six weeks prior to study enrollment.
* Indications of substance or alcohol abuse within the last 3 years
* All forms of smoking (e.g. vaping, cigarette, cannabis)
* Current enrollee in a clinical research study.
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