The Effect of Nocturnal Dexmedetomidine on Postoperative Sleep Quality and Fatigue After Major Surgery in Elderly Patients: DEXSLEEP Study

Recruiting Phase 4 Interventional Study
Postoperative Fatigue Postoperative Sleep Disturbances Surgical Stress Response
Prior Safety Data This treatment has already been tested in at least one earlier human trial.
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At a Glance
Age
60 and older
Sex
Any
Trial phase
Phase 4
Study type
Interventional
Purpose
Treatment
Participants needed
102 (estimated)
Sponsor
Ziekenhuis Oost-Limburg · Other
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About This Trial
In the aftermath of major surgery, many patients suffer from pain, fatigue, reduced general well-being, and cognitive dysfunction. Another common concern after major surgery is sleep impairment and there is little known about its effect on postoperative morbidity, especially postoperative fatigue and muscle function. Dexmedetomidine has been shown to possibly improve postoperative sleep quality i…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * aged 60 years or older; * scheduled for thoracoscopic lung surgery. Exclusion Criteria: * lack of informed consent or inability to give informed consent; * ≥ 2nd-degree atrioventricular block without pacemaker; * uncontrolled hypotension (blood pressure \< 90/60 mmHg); * …
Contacts

Steven Thiessen

3289325294

steven.thiessen@zol.be

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