Neurofeedback for Depression and Suicidal Thoughts in Veterans
Suicide Specific Rumination in Veterans
Recruiting
N/AInterventional Study
DepressionSuicideMood Disorders
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Ready to participate?
Review the details below, then apply to join this clinical trial.
At a Glance
Age
18 – 65
Sex
Any
Study type
Interventional
Purpose
Other
Participants needed
15 (estimated)
Sponsor
VA Office of Research and Development · Federal
Who this trial is looking for
This trial is looking for veterans aged 18-65 who have experienced suicidal thoughts. Participants will learn how to manage their brain activity with real-time feedback while receiving mental health treatment.
Are You a Good Fit for This Trial?
You may be able to join if
I am a U.S. military veteran between 18-65 years old.
I have a score of 10 or more on the Suicide Rumination Scale.
I am stable on my mental health medications.
I am engaged in mental health care treatment.
I can give written consent.
I have a negative pregnancy test on MRI scan days.
You may not be able to join if
I have a major medical or neurological disorder that could interfere with treatment.
I have had a moderate or severe traumatic brain injury.
I am at imminent risk of suicide.
I have a current psychotic disorder.
I have any MRI contraindications.
I have a moderate or severe substance use disorder for any substance other than cannabis or alcohol.
I am pregnant or trying to become pregnant.
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer a few quick questions to see if you may meet the eligibility requirements.
Few treatments target core features of suicidal thoughts and behaviors in Veterans. Real-time functional magnetic resonance imaging neurofeedback can provide information regarding brain activation associated with suicide-specific rumination, defined as a "repetitive mental fixation on one's suicidal thoughts and intentions." The goal of this feasibility study is for Veterans to learn strategies fo…
Few treatments target core features of suicidal thoughts and behaviors in Veterans. Real-time functional magnetic resonance imaging neurofeedback can provide information regarding brain activation associated with suicide-specific rumination, defined as a "repetitive mental fixation on one's suicidal thoughts and intentions." The goal of this feasibility study is for Veterans to learn strategies for modulating activity within brain regions that have been demonstrated to contribute to the maintenance of rumination, as they receive neurofeedback feedback signals from the brain.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* U.S. military veteran between 18-65 years old
* negative pregnancy test on MRI scan days
* score greater than or equal to 10 on the Suicide Rumination Scale
* clinically stabilized on psychotropic medications
* engaged in mental health care treatment
* able to provide written,…
Inclusion Criteria:
* U.S. military veteran between 18-65 years old
* negative pregnancy test on MRI scan days
* score greater than or equal to 10 on the Suicide Rumination Scale
* clinically stabilized on psychotropic medications
* engaged in mental health care treatment
* able to provide written, informed consent
Exclusion Criteria:
* no major medical or neurological disorders that could interfere with treatment
* moderate or severe traumatic brain injury
* current imminent suicide risk, as determined through psychiatric interview, responses to C-SSRS, and clinical judgment of the assessor
* any current psychotic disorder
* MRI contraindications
* any substance use disorder for substances other than cannabis or alcohol (mild alcohol or cannabis use disorder does not exclude participants but moderate or severe alcohol or cannabis substance use disorder is disqualifying)
* pregnant or trying to become pregnant
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