Repetitive Transcranial Magnetic Stimulation and Postoperative Neurocognitive Recovery
Recruiting
N/A
Interventional Study
Older Patients
Cognitive Impairment
Repetitive Transcranial Magnetic Stimulation
Delayed Neurocognitive Recovery
Postoperative Neurocognitive Disorder
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
At a Glance
- Age
- 65 and older
- Sex
- Any
- Study type
- Interventional
- Purpose
- Prevention
- Participants needed
- 568 (estimated)
- Sponsor
- Peking University First Hospital · Other
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About This Trial
Patients with preoperative cognitive impairment are at increased risks of delayed neurocognitive recovery (DNR) and postoperative neurocognitive disorder (POCD). Repetitive transcranial magnetic stimulation (rTMS) has been used to improve cognitive function in patients with cognitive impairement. This trial is designed to compare the effects of rTMS versus sham intervention on postoperative neuroc…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
1. Aged ≥65 years;
2. Patients with preoperative mild to moderate cognitive impairment, defined as 9\<Montreal Cognitive Assessment (MoCA)\<26;
3. Scheduled for elective non-cardiac surgery under general anesthesia, with an expected surgical duration of \>2 hours;
4. Expected to…
Contacts