Exercise for Walking Problems in MCI and Alzheimer's

Locomotion Adaptation Deficits in Older Adults With Mild Cognitive Impairment and Alzheimers Disease

Recruiting N/A Interventional Study
Alzheimers Disease Mild Cognitive Impairment
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
50 – 90
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
10 (estimated)
Sponsor
Emory University · Other
Who this trial is looking for

This trial is looking for older adults with Mild Cognitive Impairment or Alzheimer's Disease to understand how these conditions affect walking. Participants will undergo assessments and may participate in exercise based interventions.

Are You a Good Fit for This Trial?
Must not be taking AntipsychoticsOpioidsStimulantsChemotherapyLevodopa
Rules you out Psychotic disordersSubstance Use DisorderMajor Depressive DisorderGeneralized Anxiety Disorder

You may be able to join if

  • I have been diagnosed with Mild Cognitive Impairment or Alzheimer's Disease.
  • I can walk 10 or more feet without an assistive device.
  • I have completed six grades of education or have a good work history.
  • I have a Mini-Mental State Exam score between 20 and 26.
  • I have a Clinical Dementia Rating score of 0.5.
  • I have evidence of impaired executive function based on the Montreal Cognitive Assessment.
  • I have not been hospitalized in the last 60 days.

You may not be able to join if

  • I have had an acute medical illness requiring hospitalization.
  • I have uncontrolled congestive heart failure.
  • I have a history of stroke.
  • I cannot perform study procedures.
  • I have severe arthritis or mobility problems.
  • I take medications that could negatively affect my cognition.
  • I have a psychotic disorder.
  • I have Major Depressive Disorder or Generalized Anxiety Disorder within the last six months.

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

Think this trial could be right for you?

Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.

Check Your Eligibility
About This Trial
In people with Mild Cognitive Impairment (MCI) and Alzheimer's Disease (AD), reduced capacity for locomotor adaptation is a fundamental but poorly understood mechanism that can be a sensitive biomarker of cognitive-motor impairments. It is also an important therapeutic target for exercise-based interventions to improve walking function. The overall goal of this study is to understand the effects o…
Trial Locations
Loading…

Loading trial locations…

Eligibility Criteria
Inclusion Criteria: * AD and MCI will be defined through formal diagnosis provided by a board-certified Neurologist. Amnestic MCI will be defined using the AD Neuroimaging Initiative (ADNI) criteria. All MCI participants in ADNI are required to have an amnestic subtype defined as: * Subjective m…
Contacts

Trisha Kesar, PT, PhD

(404) 712-5803

tkesar@emory.edu

CONTACT