An Open-label Phase I/II Study of JR-446 in Mucopolysaccharidosis Type IIIB

Recruiting Phase 1 Phase 2 Interventional Study
Mucopolysaccharidosis III-B
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Prior Safety Data This treatment has already been tested in at least one earlier human trial.
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At a Glance
Age
Up to 17
Sex
Any
Trial phase
Phase 1/2
Study type
Interventional
Purpose
Treatment
Participants needed
10 (estimated)
Sponsor
JCR Pharmaceuticals Co., Ltd. · Industry
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About This Trial

A Phase I/ II, open-label study, designed to evaluate the safety and explore efficacy of the study drug in development for the treatment of MPS IIIB patients.

Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Chronological age of \<18 years * Confirmed diagnosis of MPS IIIB Exclusion Criteria: * Prior experience to gene therapy or HSCT with successful engraftment * Past use of another investigational drug or product in last 4 months or 5 half-lives (whichever is longer) before si…
Contacts

JCR Pharmaceuticals Co., Ltd.

+81-797-32-8582

clinical_development@jp.jcrpharm.com

CONTACT