Fecal Amino Acids Study for Irritable Bowel Syndrome
Fecal Amino Acids,Gut Taste Receptors and Irritable Bowel Syndromes
Recruiting
Observational Study
Irritable Bowel Syndrome
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
Ready to participate?
Review the details below, then apply to join this clinical trial.
At a Glance
Age
18 – 80
Sex
Any
Study type
Observational
Participants needed
100 (estimated)
Sponsor
Second Affiliated Hospital of Xi'an Jiaotong University · Other
Who this trial is looking for
This trial is looking for adults with Irritable Bowel Syndrome (IBS) to study how amino acids in feces may relate to their symptoms. Participants will provide samples of their feces and intestinal tissues for analysis.
Are You a Good Fit for This Trial?
You may be able to join if
I have been diagnosed with IBS based on the Rome IV criteria.
I am at least 18 years old.
You may not be able to join if
I have a history of celiac disease or other serious intestinal diseases.
I have serious neurological or psychiatric conditions.
I have had abdominal surgery.
I am pregnant, possibly pregnant, or breastfeeding.
I have had a colonoscopy in the past year.
I have chosen not to participate in the study.
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer a few quick questions to see if you may meet the eligibility requirements.
Clinical data, fresh feces and intestinal mucosal tissues of patients with diarrheal IBS were collected. High performance liquid chromatography, immunohistochemistry and immunofluorescence were used to study the amino acid levels in feces of patients with IBS, the expression of taste receptors in intestinal mucosa, and the correlation between symptoms of abdominal pain and diarrhea and the express…
Clinical data, fresh feces and intestinal mucosal tissues of patients with diarrheal IBS were collected. High performance liquid chromatography, immunohistochemistry and immunofluorescence were used to study the amino acid levels in feces of patients with IBS, the expression of taste receptors in intestinal mucosa, and the correlation between symptoms of abdominal pain and diarrhea and the expression of taste receptors, so as to obtain the conclusion that "intestinal amino acid perception abnormalities exist in patients with IBS. And correlated with clinical symptoms."
Trial Locations
Loading…
Loading trial locations…
Facility
City
State
Country
Status
Eligibility Criteria
Inclusion Criteria:
* Patients with IBS who meet the Rome IV diagnostic criteria:
1. that is, recurrent abdominal pain, with symptoms occurring at least 1 day per week or at least 3 days per month on average in the last 3 months, combining 2 or more of the following:
1. related to defecati…
Inclusion Criteria:
* Patients with IBS who meet the Rome IV diagnostic criteria:
1. that is, recurrent abdominal pain, with symptoms occurring at least 1 day per week or at least 3 days per month on average in the last 3 months, combining 2 or more of the following:
1. related to defecation;
2. accompanied by changes in the frequency of bowel movements;
3. Accompanied by changes in fecal characteristics (appearance). (Symptoms appeared at least 6 months before diagnosis, and above diagnostic criteria were met in the last 3 months) 2. Age ≥18 years old.
Exclusion Criteria:
* 1\. History of celiac disease and other organic intestinal diseases, metabolic diseases (thyroid dysfunction, diabetes, etc.); (2) Serious neurological, mental and psychological diseases, or accompanied by serious organ dysfunction; 3. Abdominal surgery; 4. Pregnant, possible pregnant and lactating patients; 5. History of colonoscopy in the past 1 year; 6. Declined to participate in the study.
Picking one helps us show the most relevant trials first.
Your results are loading in the background — you can
change this any time from the results page.
Set your location to continue
Find My Trials uses your location to surface clinical trials near you.
Add your city or zip code to your profile and try again.