Spine Unit Modelling Coupled With hIgh Throughput Analysis (SUIT)
Recruiting
Observational Study
Degenerative Disc Disease
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 18 – 60
- Sex
- Any
- Study type
- Observational
- Participants needed
- 20 (estimated)
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio · Other
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About This Trial
Ageing and inflammation represent two main drivers of DDD, a progressive, chronic condition involving vertebral bone, cartilaginous endplate and intervertebral disc.
In vitro investigation of the DDD-associated processes on single compartments of the spine unit or ex vivo animal models fail in recapitulating the complex spine pathophysiology or suffer from inter-species differences. Given these p…
Trial Locations
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Eligibility Criteria
DDD patients:
* Signature of the Informed Consent for the study
* Age 30-60 years (included)
* Pfirrmann grade III-V
* Need to undergo spinal surgery
Subjects for the isolation of adipose-derived MSCs:
* Signature of the Informed Consent for the study
* Age 18-50 (included)
* Need to undergo surg…
Contacts
No contact information available.