Cryocompression With or Without Cilostazol for the Prevention of Paclitaxel-induced Neuropathy in Patients With Gynecological Cancers

Recruiting Phase 2 Interventional Study
Cervical Carcinoma Fallopian Tube Carcinoma Malignant Solid Neoplasm Malignant Uterine Neoplasm Ovarian Carcinoma Primary Peritoneal Carcinoma Vulvar Carcinoma
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Prior Safety Data This treatment has already been tested in at least one earlier human trial.
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At a Glance
Age
18 and older
Sex
Female
Trial phase
Phase 2
Study type
Interventional
Purpose
Supportive Care
Participants needed
70 (estimated)
Sponsor
Emory University · Other
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About This Trial
The phase II trial evaluates the effectiveness of cryocompression therapy alone or in combination with cilostazol in preventing paclitaxel-induced peripheral neuropathy (numbness, pain or tingling in the feet and hands) for patients with gynecologic cancers. Peripheral neuropathy is a common side effect of many chemotherapeutic agents, including paclitaxel. Paclitaxel is in a class of medications …
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * INCLUSION CRITERIA FOR ARMS A and B: * Age 18 years or older * Diagnosis of uterine, ovarian/fallopian tube/primary peritoneal, cervical, or vulvar cancer and planned chemotherapy regimen of 6-9 cycles of paclitaxel and carboplatin or cisplatin with or without VEGF inhibition,…
Contacts

Susan Modesitt, MD

404-727-9578

smodesi@emory.edu

CONTACT

Sharese Windley

404-778-8778

sharese.windley@emory.edu

CONTACT