No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
Ready to participate?
Review the details below, then apply to join this clinical trial.
At a Glance
Age
18 – 89
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
138 (estimated)
Sponsor
Emory University · Other
Who this trial is looking for
This trial is looking for people with Multiple Sclerosis who have dizziness or imbalance. Participants will do daily gaze stabilization exercises to see if they help more than less frequent training.
Are You a Good Fit for This Trial?
Rules you outClinically isolated syndromeRadiologically isolated syndromeVestibular Migraine
You may be able to join if
I have been diagnosed with Multiple Sclerosis
I speak and understand English
I have dizziness, imbalance, or have fallen at least twice in the past year
I am a healthy volunteer without MS or related conditions
You may not be able to join if
I have worsening MS symptoms in the last 60 days
I have changed my immunotherapy in the last 60 days
I have cognitive impairment that affects my daily living
My blood pressure is above the normal range
I have poor vision that can't be corrected
I have significant eye misalignment or related eye issues
I am currently pregnant or may become pregnant
I am in vestibular rehabilitation for dizziness
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
The study aims to study the effects of a novel treatment for vestibular symptoms in people with multiple sclerosis. The main objective is to determine whether daily personalized gaze stabilization training is more beneficial than intermittent gaze stability training in people with multiple sclerosis.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Neurologist-confirmed diagnosis of primary progressive or relapsing and remitting MS per The 2017 Revision of the McDonald Criteria and the Magnetic Resonance Imaging in MS, or a healthy volunteer without a diagnosis of multiple sclerosis or any related neurological conditions…
Inclusion Criteria:
* Neurologist-confirmed diagnosis of primary progressive or relapsing and remitting MS per The 2017 Revision of the McDonald Criteria and the Magnetic Resonance Imaging in MS, or a healthy volunteer without a diagnosis of multiple sclerosis or any related neurological conditions
* Fluent in speaking and understanding English
* Subjects with multiple sclerosis have self-reported vestibular symptoms of dizziness, imbalance, and/or a history of at least two falls in the prior 12 months
Exclusion Criteria:
* Clinically isolated syndrome or radiologically isolated syndrome.
* Worsening MS symptoms during the prior 60 days
* Immunotherapy change in the prior 60 days
* Self-reported cognitive impairment that limits independence with basic and instrumental activities of daily living
* Systolic blood pressure \> 180 mmHg and/or diastolic blood pressure \> 90 mmHg at rest
* Static visual acuity with correction of worse than 1.0 logMAR
* Manifest ocular misalignment ≥ 5 diopters (e.g., tropia, lazy eye, strabismus}
* Convergence insufficiency
* Intra-nuclear ophthalmoplegia
* Vestibular Migraine
* Major orthopedic conditions that limit cervical spine range of motion or that alter walking
* Self-reported current or potential for pregnancy during enrollment
* Ongoing participation in vestibular rehabilitation for dizziness
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