CNKSR2 Natural History Study

Recruiting Observational Study
Developmental Dysphasia Epileptic Encephalopathy, Childhood-Onset X-Linked Intellectual Disability
No Study Drug Researchers observe your health over time — no experimental treatment is given.
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At a Glance
Age
6 – 21
Sex
Any
Study type
Observational
Participants needed
15 (estimated)
Sponsor
University of California, San Francisco · Other
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About This Trial
This prospective natural history study is being conducted to define the electroclinical, neurodevelopmental, and behavioral characteristics of CNKSR2 epilepsy aphasia syndrome (EAS) and intellectual disability (ID) in children aged 6 to 21 years old with CNKSR2 mutations. The data collected from this study will serve as an external control to eventual clinical trials examining precision medicine …
Trial Locations
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Eligibility Criteria
Inclusion Criteria: 1. Age between 6 and 21 years (inclusive) at time of consent. 2. Confirmed CNKSR2 mutation, as demonstrated by genetic testing and confirmed by the investigators. 3. Confirmed intellectual disability or developmental delays, as defined by the American Academy of Pediatrics (Moes…
Contacts

Alex Fay, MD, PhD

415-353-7596

alexander.fay@ucsf.edu

CONTACT

Maya Dhar, MS

415-353-9465

maya.dhar@ucsf.edu

CONTACT