Genetic and Epigenetic Background of Inner Ear Dysfunction in Turner Syndrome

Recruiting Observational Study
Sensorineural Hearing Loss Turner Syndrome Inner Ear Disease
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Healthy Volunteers Welcome You do not need to have the condition being studied to take part. No Study Drug Researchers observe your health over time — no experimental treatment is given.
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At a Glance
Age
18 – 60
Sex
Female
Study type
Observational
Participants needed
150 (estimated)
Sponsor
Gødstrup Hospital · Other
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About This Trial
The goal of this case-control study is to pave the way for new revolutionary treatment measures within hearing loss that could either replace or delay the need for hearing aids. The study focuses on people with Turner syndrome (TS). The aim is to find out if there are specific DNA methylation patterns and/or RNA expression profiles linked to sensorineural hearing loss (SNHL) in people with TS. Ad…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * age between 18 and 60 years old Exclusion Criteria: * Contraindications for the MRI or CBCT * Serious medical disorders * Neurological or psychiatric disorders of any kind * Use of medication that is known to influence inner ear function * Medical history with dizziness or h…
Contacts

Louise Hill-Madsen, MD

20282635

lohill@rm.dk

CONTACT