Methacholine Challenge Test (MCT) in Healthy Adults
Recruiting
Observational Study
Hyperreactive Airway Disease
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 18 – 65
- Sex
- Any
- Study type
- Observational
- Participants needed
- 25 (estimated)
- Sponsor
- Allergi- og Lungeklinikken, Elsinore · Research network
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About This Trial
Knowledge of Methacholine Challenge Test (MCT) and impedance Oscillometry (IOS) is limited. Only three studies have included adult patients, and none of these with healthy controls. The three studies have combined IOS and spirometry in the same test, although it is not recommended to perform IOS after a test that requires deep breathing, e.g. FEV1 measurement. Deep breathing is considered to affec…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Forced expiratory volume in the 1. second (FEV1) \>80%
* FEV1/FVC-ratio \>0,7
* FeNO \<25 pbb
* Oxygen saturation (SatO2) \>95%
* Negative methacholine Challenge Test = drop in FEV1 less than 20%
Exclusion Criteria:
* Any lung disease
* Lung symptoms
* Medicine for lung dise…
Contacts