Establishing Reference Ranges for Fat-Soluble Vitamins in Healthy Chinese Adults

Inclusion Criteria: 1. Age ≥ 18 years old, both male and female; 2. Undergo a health examination in this hospital and consciously maintain good physical health; 3. Voluntarily participate in this study and sign an informed consent form; 4. No acute and chronic diseases: no acute and chronic infections, cardiovascular and cerebrovascular diseases, diabetes, respiratory diseases, urinary diseases, thyroid diseases, digestive diseases, rheumatic diseases, blood system diseases, tumors, pituitary dysfunction; No hepatitis B, hepatitis C virus, or acquired immunodeficiency syndrome; 5. Blood pressure: systolic blood pressure\<140 mmHg and diastolic blood pressure\<90 mmHg; 6. BMI (body mass index):\<28 kg/m2 and ≥ 18.5 kg/m2; 7. No surgery was performed within 6 months, no blood donation, transfusion, or significant blood loss occurred within 4 months; 8. No long-term medication history, no medication or vitamin supplements taken within 2 weeks; 9. Women who are not pregnant, breastfeeding, or within one year after childbirth; 10. No alcohol abuse (alcohol consumption but alcohol intake\<140 g/week for males and\<70 g/week for females), and smoking (\<20 cigarettes/day). Exclusion Criteria: 1. Serum alanine aminotransferase (ALT): Male\>50 U/L, female\>40 U/L; Or serum gamma glutamyltransferase (GGT): male\>60 U/L, female\>45 U/L; Or serum aspartate aminotransferase (AST): male\>40 U/L, female\>35 U/L; Or serum alkaline phosphatase (ALP): male\>125 U/L, female (20-49 years old)\>100 U/L, female (50-79 years old)\>100 U/L; 2. Serum albumin (ALB) \< 40 g/L; 3. Serum creatinine (SCr): Male (20-59 years old)\>97 μ mol/L, male (60-79 years old)\>111 μ mol/L; Female (20-59 years old)\>73 μ mol/L, female (60-79 years old)\>81 μ mol/L; 4. Fasting blood glucose (FBG) ≥ 7.0 mmol/L; 5. White blood cell count (WBC): \< 3.5 × 109/L or \> 9.5 × 109/L; 6. Hemoglobin (Hb): Male \< 120 g/L; Female\<110 g/L; 7. Glycated hemoglobin (HbA1c)\<4% or\>6%; 8. Total cholesterol (TC) ≥ 5.2 mmol/L; Or triglycerides (TG) ≥ 1.7 mmol/L; 9. Low density lipoprotein cholesterol (LDL-C) ≥ 3.4 mmol/L; Or high-density lipoprotein cholesterol (HDL-C)\<1.0 mmol/L; 10. Serum uric acid (UA)\>420 μ mol/L.