Ventilator Pressure and Optimization of Compliance and Hemodynamics
Recruiting
N/A
Interventional Study
Bronchopulmonary Dysplasia
Pulmonary Hypertension Due to Lung Diseases and Hypoxia
Extreme Prematurity
Ventilator Lung; Newborn
Ventilation Perfusion Mismatch
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
At a Glance
- Age
- 7 Days – 30 Days
- Sex
- Any
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 24 (estimated)
- Sponsor
- University of Alabama at Birmingham · Other
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About This Trial
In preterm infants \< 34 weeks' gestation at birth receiving respiratory support with invasive positive pressure ventilation, the positive end-expiratory pressure (PEEP) of best compliance will increase the cardiac output and improve oxygenation. This study may emphasize using point-of-care echocardiography along with electrical impedance tomography (EIT) to optimize ventilator settings in preterm…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
Preterm infants with recovering respiratory distress syndrome (RDS) who were born at a gestational age \< 34 weeks and are receiving respiratory support via conventional mechanical ventilation or on HFJV.
* Post-natal age \> 7 days and less than 1 month (outside golden week pro…
Contacts