Prognostic Biomarkers for Pulpotomy Outcome
Recruiting
N/A
Interventional Study
Pulpitis - Irreversible
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
At a Glance
- Sex
- Any
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 192 (estimated)
- Sponsor
- The University of Hong Kong · Other
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About This Trial
This study will recruit 180 molars diagnosed with irreversible pulpitis. Full pulpotomy will be performed on 120 teeth, while RCT (root canal treatment) will be conducted on another cohort of 60 teeth as the control for assessing long-term outcomes. Additionally, 12 blood samples and pulp tissues from healthy teeth receiving elective RCT will be collected as the controls. The first pulpal blood sa…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Permanent molars showing clinical and radiographic evidence of a deep carious lesion (extend to the three-quarters thickness of dentine radiographically) extending close to the pulp chamber
* Clinical diagnosis of irreversible pulpitis, including spontaneous pain, lingering pa…
Contacts