Exploratory Clinical Study of SHR-0302 and SHR-2554 in Patients With Relapsed/Refractory Peripheral T Cell Lymphoma

Recruiting Phase 2 Interventional Study
Relapsed/Refractory Peripheral T Cell Lymphoma
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Prior Safety Data This treatment has already been tested in at least one earlier human trial.
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At a Glance
Age
18 – 70
Sex
Any
Trial phase
Phase 2
Study type
Interventional
Purpose
Treatment
Participants needed
25 (estimated)
Sponsor
Fudan University · Other
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About This Trial
This is an open-label, prospective and exploratory clinical study to evaluate the efficacy and safety of JAK inhibitor SHR-0302 in combination with EZH2 inhibitor SHR-2554 in patients with R/R PTCL. The study plans to enroll approximately 25 patients. 6-12 patients will receive SHR-0302 monotherapy and SHR-0302+SHR-2554 combination therapy in the safety run-in phase. According to the safety observ…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Males or females aged 18-70 years (inclusive); * Histologically confirmed peripheral T-cell lymphoma; * Disease status defined as relapsed or refractory after \>=1 prior systemic treatment lines; * Have measurable lesions; * ECOG performance status must be 0 or 1 and has not d…
Contacts

Rong Tao, MD

8621-64175590

rtao@shca.org.cn

CONTACT

Chuanxu Liu, MD

8621-64175590

liuchuanxu@shca.org.cn

CONTACT