Exploratory Clinical Study of SHR-0302 and SHR-2554 in Patients With Relapsed/Refractory Peripheral T Cell Lymphoma
Recruiting
Phase 2
Interventional Study
Relapsed/Refractory Peripheral T Cell Lymphoma
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Prior Safety Data
This treatment has already been tested in at least one earlier human trial.
At a Glance
- Age
- 18 – 70
- Sex
- Any
- Trial phase
- Phase 2
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 25 (estimated)
- Sponsor
- Fudan University · Other
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About This Trial
This is an open-label, prospective and exploratory clinical study to evaluate the efficacy and safety of JAK inhibitor SHR-0302 in combination with EZH2 inhibitor SHR-2554 in patients with R/R PTCL. The study plans to enroll approximately 25 patients. 6-12 patients will receive SHR-0302 monotherapy and SHR-0302+SHR-2554 combination therapy in the safety run-in phase. According to the safety observ…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Males or females aged 18-70 years (inclusive);
* Histologically confirmed peripheral T-cell lymphoma;
* Disease status defined as relapsed or refractory after \>=1 prior systemic treatment lines;
* Have measurable lesions;
* ECOG performance status must be 0 or 1 and has not d…
Contacts