Fiber and Calcium Absorption in Older Men
Recruiting
Phase 2
Interventional Study
Aging
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Prior Safety Data
This treatment has already been tested in at least one earlier human trial.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
At a Glance
- Age
- 60 and older
- Sex
- Male
- Trial phase
- Phase 2
- Study type
- Interventional
- Purpose
- Other
- Participants needed
- 30 (estimated)
- Sponsor
- VA Office of Research and Development · Federal
Think this trial could be right for you?
Answer a few quick questions to see if you may meet the eligibility requirements.
Check Your Eligibility
About This Trial
Osteoporotic fractures are a major but underrecognized problem in men. There is growing evidence that low dietary fiber intake is a modifiable risk factor for age-related bone loss in men. Preclinical and human studies in adolescents and postmenopausal women suggest that dietary fiber intake influences bone metabolism by modulating the gut microbiome to augment intestinal calcium absorption, but i…
Trial Locations
Loading…
Loading trial locations…
Eligibility Criteria
Inclusion Criteria:
* Male Veterans 60 years of age
Exclusion Criteria:
* History of malabsorption
* Hypercalcemia (corrected Ca \> 10.2 mg/dL)
* Vitamin D insufficiency (25OHD \< 30 ng/mL)
* Chronic kidney disease stage 3B or worse (CrCl \< 45 mL/min)
* Severe hypogonadism (AM fasting serum tota…
Contacts