The Aim of This Study is to Determine if Oocyte Sorting for Group Culture Using an Artificial Intelligence Image Analysis Tool (MagentaTM) Increases the Usable Blastocyst Yield and Subsequent Pregnancy in Patients Undergoing IVF
Recruiting
Observational Study
Infertility Primary
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
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At a Glance
Sex
Any
Study type
Observational
Participants needed
450 (estimated)
Sponsor
Ovation Fertility · Other
Who this trial is looking for
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The aim of this study is to determine if oocyte sorting for group culture using an artificial intelligence image analysis tool (MagentaTM) increases the usable blastocyst yield and subsequent pregnancy in patients undergoing IVF.
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Eligibility Criteria
Inclusion Criteria:
* Fresh MII oocytes
* ICSI cycles with patient's or donor's sperm
* Patient's or donor's oocytes
* Full IVF cycle information available (including total number of oocytes retrieved, total MII oocytes, fertilization, embryo and blastocyst development, as well as ploidy status or …
Inclusion Criteria:
* Fresh MII oocytes
* ICSI cycles with patient's or donor's sperm
* Patient's or donor's oocytes
* Full IVF cycle information available (including total number of oocytes retrieved, total MII oocytes, fertilization, embryo and blastocyst development, as well as ploidy status or implantation results, and 6-7 week ultrasound, if applicable)
* Good quality images of MII oocytes taken with a specified camera (Basler) and Future Fertility Software
* Single embryo transfers (SETs) at blastocyst stage.
* Blastocyst freeze-all cycles
Exclusion Criteria:
* Severe male factor infertility (\<1 million motile), including surgically retrieved sperm.
* ICSI cycles inseminating in vitro matured (IVM) oocytes
* Rescue ICSI oocytes (oocytes failed standard IVF and are re-inseminated by ICSI)
* Low quality images - Poor quality images on day of upload or before unblinding
* Lack of correlating reproductive outcomes (full IVF lab results not available).
* Autologous or donor frozen/warmed oocytes
* Day 3 embryo transfers or cleavage stage embryo freezing
* Patients with less than 6 mature oocytes
Contacts
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