Increasing the Repertoire of Intermuscular Co-ordination Post Stroke Through EMG-Guided Human-Machine Interaction
Recruiting
N/AInterventional Study
Stroke
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
Ready to participate?
Review the details below, then apply to join this clinical trial.
At a Glance
Age
40 – 75
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
74 (estimated)
Sponsor
University of Houston · Other
Who this trial is looking for
This trial is looking for people who have had a stroke to see if an exercise program can help improve muscle coordination. Participants will engage in non-invasive exercises guided by muscle activity readings.
Are You a Good Fit for This Trial?
Must be takingAnti-spasticity medication
You may be able to join if
I am between 40 and 75 years old.
I have had a stroke that affects one side of my body.
I have been stable for more than 6 months after my stroke.
I am on stable medication without changes for at least 3 months.
I have low spasticity in my affected arm.
I have not received botulinum toxin treatment in my affected arm in the last 3 months.
You may not be able to join if
I have an orthopedic disorder affecting my arms.
I have a cognitive impairment that affects my ability to consent.
I have a history of another neurologic disease.
I have lost the ability to sense joint position in my arms.
I am pregnant or might be pregnant.
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer a few quick questions to see if you may meet the eligibility requirements.
The purposes of this study include:
1. \- To identify whether features of aberrant intermuscular coordination patterns can be used to predict motor impairment after stroke.
2. \- To test whether muscle synergies are malleable to a non-invasive EMG-guided exercise that induces changes in intermuscular coordination of upper extremity muscles after stroke.
Trial Locations
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Eligibility Criteria
Inclusion criteria for aged matched healthy group
* Male or female whose age range between 40 and 75
* no known neurological injuries
Exclusion criteria for aged matched healthy group
* have an orthopedic disorder involving upper limbs;
* have a history of any neurologic disease;
* have any histo…
Inclusion criteria for aged matched healthy group
* Male or female whose age range between 40 and 75
* no known neurological injuries
Exclusion criteria for aged matched healthy group
* have an orthopedic disorder involving upper limbs;
* have a history of any neurologic disease;
* have any history of epilepsy of the potential participants and/or their family members;
* are unable to consent;
* are pregnant.
Inclusion criteria for stroke group
* male or female hemiparetic chronic stroke survivors;
* age ranging between 40-75 year;
* with single unilateral ischemic or hemorrhagic middle cerebral artery stroke;
* neurologically stable for \>6 months;
* have an expectation that current medication will be maintained without changes for at least 3 months. Stable use of anti-spasticity medication (e.g., baclofen, diazepam, tizanidine) is accepted;
* without severe spasticity (Modified Ashworth (MA) \<4);
* have not received botulinum toxin on the impaired arm within 3 months.
Exclusion criteria for stroke group
* have an orthopedic disorder involving upper limbs;
* cognitive impairment sufficient to interfere with informed consent or successful completion of the protocol (Montreal Cognitive Assessment (MoCA) score \< 26);
* a history of another neurologic disease;
* anesthesia of joint position sense in upper limbs;
* are pregnant or have a chance that they might be (self-reported);
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