Microclots and Neutrophil Activation as Potential Indicators for Stroke Risk and Reperfusion Failure

Recruiting Observational Study
Ischemic Stroke
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Healthy Volunteers Welcome You do not need to have the condition being studied to take part. No Study Drug Researchers observe your health over time — no experimental treatment is given.
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At a Glance
Age
18 and older
Sex
Any
Study type
Observational
Participants needed
500 (estimated)
Sponsor
University of Zurich · Other
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About This Trial
Stroke remains a major health burden worldwide. Many patients are severely disabled and stay in need of care. Mechanical thrombectomy has dramatically improved outcomes for stroke patients with large vessel occlusions, yet 40-50% of patients with successful recanalization remain severely disabled despite successful recanalization, a scenario called "futile recanalization". One of the causes for th…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: Patients without acute stroke CS or CSG * No previous stroke or previous stroke ≥ 1 year ago * Signed informed consent Patients with acute stroke (AS-noTx, AS-IVT, AS-MT): * Patients admitted with high suspicion of acute ischemic stroke * Time of onset of stroke symptoms ≤ 12…
Contacts

Lukas Otto, Dr. med.

+41 43 253 13 01

lukasbastian.otto@usz.ch

CONTACT

Susanne Wegener, Prof.

+41 44 255 10 78

susanne.wegener@usz.ch

CONTACT