California Grapes for Gut and Heart Health
Prebiotic Effects of California Grapes on Gut Health and Cardiometabolic Health in Overweight Men and Women
Recruiting
N/A
Interventional Study
Arterial Stiffness
Blood Pressure
Dysbiosis
Inflammation
Permeability; Increased
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
At a Glance
- Age
- 45 – 70
- Sex
- Any
- Study type
- Interventional
- Purpose
- Prevention
- Participants needed
- 40 (estimated)
- Sponsor
- University of California, Davis · Other
Who this trial is looking for
This trial is looking for overweight men and women aged 45-70. Participants will take grape powder twice a day for three weeks to see how it affects gut and heart health.
Are You a Good Fit for This Trial?
You may be able to join if
- I am a post-menopausal woman
- I am overweight or obese
- I have stable type 2 diabetes or metabolic syndrome
- I can understand and agree to participate
- I am willing to follow the study procedures
- I can provide stool and blood samples
You may not be able to join if
- I have started menopause hormone therapy in the last 6 months
- I have taken antibiotics or prebiotics in the last 3 months
- I take insulin for diabetes
- I am vegetarian or vegan and cannot follow the modified diet
- I have any serious medical condition like heart disease or cancer
- I have a psychiatric condition affecting my understanding of the study
- I have had an eating disorder in the last 5 years
- I smoke or have smoked in the last 180 days
Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
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About This Trial
The goal of this clinical trial is to assess the impact of table grape consumption on gut microbiome, intestinal permeability, systemic inflammation, and vascular function in healthy overweight men and women aged 45-70 years. The main questions it aims to answer are:
* Does daily grape intake alter intestinal microbiome composition and intestinal permeability?
* Are changes in gut microbiota and …
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* post-menopausal women (cessation of menstruation for minimum two years)
* overweight and obese (BMI between 25-35 kg/m2)
* stable treatment for type 2 diabetes or metabolic syndrome
* ability to understand the intervention concept and written consent to participate
* willingne…
Contacts