XB010 for Advanced Solid Tumors

Study of XB010 in Subjects With Solid Tumors

Recruiting Phase 1 Interventional Study
Locally Advanced or Metastatic Solid Tumors Esophageal Squamous Cell Cancer Head and Neck Squamous Cell Cancer NSCLC (Non-small Cell Lung Cancer) Hormone-receptor-positive Breast Cancer Triple Negative Breast Cancer (TNBC)
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
18 and older
Sex
Any
Trial phase
Phase 1
Study type
Interventional
Purpose
Treatment
Participants needed
396 (estimated)
Sponsor
Exelixis · Industry
Who this trial is looking for

This trial is looking for adult patients with advanced solid tumors that cannot be treated with other options. Participants will receive XB010 alone or combined with another treatment called pembrolizumab to see how well it works and how safe it is.

Are You a Good Fit for This Trial?

You may be able to join if

  • I am 18 years old or older.
  • I have a performance status of 0-1.
  • I have enough healthy organ and bone marrow function.
  • I have a confirmed diagnosis of an advanced or recurrent solid tumor.

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

Think this trial could be right for you?

Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.

Check Your Eligibility
About This Trial

This is a FIH study is to evaluate the safety, tolerability, PK, immunogenicity, and preliminary antitumor activity of XB010 as a single agent and in combination with pembrolizumab in subjects with locally advanced or metastatic solid tumors for whom alternative therapies do not exist or available therapies are intolerable or no longer effective.

Trial Locations
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Eligibility Criteria
* Age 18 years or older on the day of consent. * Eastern Cooperative Oncology Group (ECOG) Performance Status of 0-1. * Adequate organ and marrow function. * Cytologically or histologically and radiologically confirmed solid tumor that is inoperable, locally advanced, metastatic, or recurrent. * …
Contacts

Exelixis Clinical Trials

1-888-EXELIXIS (888-393-5494)

druginfo@exelixis.com

CONTACT

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650-837-7400

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