Cardio and Renovascular Effects of Isometric Exercise in the Healthy Human Measured by PET/CT and MRI
Recruiting
N/A
Interventional Study
Kidneys
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
At a Glance
- Age
- 18 – 60
- Sex
- Male
- Study type
- Interventional
- Purpose
- Basic Science
- Participants needed
- 10 (estimated)
- Sponsor
- Bispebjerg Hospital · Other
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About This Trial
This randomized crossover study aims to validate measurements of renal perfusion in healthy males with PET/CT, using 15-oxygen labeled water as tracer, against the validated multiparametric MRI technique.
The study will determine:
* Total renal blood flow and regional renal perfusion at baseline (rest) and during isometric muscle exercise of the upper arm, using PET/CT (with 15-oxygen labeled wa…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Normal health stated through medical questionnaire, examination and blood samples.
Exclusion Criteria:
* Immunosuppressive treatment
* Alcohol abuse
* Treatment with glucocorticoids, Glucagon-like peptide-1 (GLP-1) agonists, dipeptidyl peptidase 4 (DPP-4)-inhibitors
* Medica…
Contacts