Effects of Ketone Supplementation on Alcohol Withdrawal and Brain Metabolism in Alcohol Use Disorder

Recruiting Phase 2 Phase 3 Interventional Study
Alcohol Use Disorder Alcohol Withdrawal Ketosis
Pivotal Trial This treatment is in the last trial phase before FDA approval. Prior Safety Data This treatment has already been tested in at least one earlier human trial.
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At a Glance
Age
18 – 65
Sex
Any
Trial phase
Phase 2/3
Study type
Interventional
Purpose
Basic Science
Participants needed
30 (estimated)
Sponsor
University of Pennsylvania · Other
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About This Trial

The goal of this clinical trial is to learn the effects of ketone supplement compared to placebo on alcohol withdrawal symptoms during a 4 day alcohol withdrawal management treatment in adults with moderate to severe alcohol use disorder at the Hospital of the University of Pennsylvania, Cedar Detox Center.

Trial Locations
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Eligibility Criteria
Inclusion Criteria: 1. Able to communicate English and provide written informed consent 2. Meets current DSM-5 criteria for moderate or severe AUD and seeking treatment for AUD 3. Minimum 3-year history of heavy drinking (self-report). 4. Presence of alcohol withdrawal (DSM-5) Exclusion Criteria: …
Contacts

Timothy Pond, MPH

215-746-1959

timpond@pennmedicine.upenn.edu

CONTACT