Establish Diagnostic and Prognostic Models for Preclinical AD Patients Based on Multimodal MRI, Behavioral, Genetic, and Plasma Biomarkers
Recruiting
Observational Study
Alzheimer Disease, Late OnsetMild Cognitive ImpairmentSubjective Cognitive Decline
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
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At a Glance
Age
50 – 79
Sex
Any
Study type
Observational
Participants needed
1,000 (estimated)
Sponsor
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School · Other
Who this trial is looking for
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To establish the diagnostic and prognostic models that could help the preclinical identification of subjects at higher risk of clinical progression to mild cognitive impairment and dementia based on combined features of baseline demographic, cognitive, behavioral, multimodal MRI, genetic, and plasma data.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* The inclusion criteria were 50-79 years old and having 8 or more years of education.
Exclusion Criteria:
* Participants with a history of stroke, other neurological disorders that could lead to cognitive impairment (Parkinson's disease, encephalitis, epilepsy, brain tumors, …
Inclusion Criteria:
* The inclusion criteria were 50-79 years old and having 8 or more years of education.
Exclusion Criteria:
* Participants with a history of stroke, other neurological disorders that could lead to cognitive impairment (Parkinson's disease, encephalitis, epilepsy, brain tumors, etc.), severe anxiety or depression, and contraindications for magnetic resonance imaging (MRI) were not enrolled.
Contacts
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