The Effect of Dexmedetomidine on the Renal Functions in Septic Critically Ill Patients
Recruiting
Phase 4
Interventional Study
Sepsis
Septic Shock
Acute Kidney Injury
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Prior Safety Data
This treatment has already been tested in at least one earlier human trial.
At a Glance
- Age
- 18 – 90
- Sex
- Any
- Trial phase
- Phase 4
- Study type
- Interventional
- Purpose
- Supportive Care
- Participants needed
- 128 (estimated)
- Sponsor
- Cairo University · Other
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About This Trial
This clinical trial aims to evaluate the effect of dexmedetomidine in Sepsis-Associated Acute Kidney Injury in critically ill patients by answering the following questions:
1. What is dexmedetomidine's effect on kidney functions?
2. What is the safety and efficacy of dexmedetomidine in Sepsis-Associated Acute Kidney Injury?
The investigator will compare dexmedetomidine to the standard sedative.
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Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Age \>21 years old
* Patients with sepsis who develop AKI within 48 hours during ICU stay
* Need for sedation due to the need for mechanical ventilation (MV) (both invasive and non- invasive) within 48 hours of AKI
Exclusion Criteria:
* Contraindications to dexmedetomidine i…
Contacts