Efficacy and Safety of Remimazolam Besylate for Sedation in Post-Non-Cardiac Surgery Patients Requiring Mechanical Ventilation
Recruiting
Phase 4
Interventional Study
Effect of Drug
Adverse Drug Event
Mechanical Ventilation Complication
Critical Illness
Surgery
Sedation
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Prior Safety Data
This treatment has already been tested in at least one earlier human trial.
At a Glance
- Age
- 18 – 64
- Sex
- Any
- Trial phase
- Phase 4
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 306 (estimated)
- Sponsor
- Beijing Shijitan Hospital, Capital Medical University · Other
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About This Trial
A multi-center, prospective, randomized, double-blind, active-controlled, no-inferiority clinical trial conducted across 5 tertiary medical centers in China. The objective of this RCT is to evaluate the sedative efficacy and safety profile of remimazolam besylate compared with dexmedetomidine in patients requiring mechanical ventilation following non-cardiac surgery. The study hypothesized that re…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Aged between 18 and 64 years
* Scheduled to undergo elective non-cardiac surgery
* Planned for general anesthesia
* With or without combined regional nerve blockade
* Admitted to the ICU with endotracheal intubation post-surgery
* With an anticipated duration of postoperative …
Contacts