Genetic Testing for Parkinson's Disease
Combined Genome and RNA Sequencing for Genetic Diagnosis of Parkinsonism
Recruiting
N/A
Interventional Study
Parkinson's Disease
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Study type
- Interventional
- Purpose
- Diagnostic
- Participants needed
- 14 (estimated)
- Sponsor
- University Hospital, Strasbourg, France · Other
Who this trial is looking for
This trial is looking for people with early-onset parkinsonism to discover genetic causes. Participants will provide samples and help researchers understand the genetics of the disease.
Are You a Good Fit for This Trial?
You may be able to join if
- I have symptoms of parkinsonism that started before age 40
- I have a family history of parkinsonism
- I have a brain scan that shows dopaminergic denervation
- DNA samples from both my asymptomatic parents are available
- I have health insurance
- I can understand the research and give my consent
You may not be able to join if
- I cannot have a skin biopsy
- I already know the genetic cause of my parkinsonism
- I have not had previous genetic testing for this condition
- I have late-onset parkinsonism starting after age 40 without family history
- I have parkinsonism linked to a specific diagnosis like toxic exposure
- I cannot receive the necessary information about the study
- I am under judicial protection
- I am under guardianship or curatorship
Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
Check Your Eligibility
About This Trial
Despite the increasing availability and advances in the analysis of high-throughput DNA sequencing, the majority of patients with early-onset or familial parkinsonism remain without a molecular diagnosis.
Studying the genetic forms of parkinsonian syndromes presents numerous clinical, scientific and therapeutic interests. In clinical practice, identifying the genetic cause in a patient allow to p…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Extrapyramidal syndrome beginning before or at the age of 40 or associated with a family history:
* Dopaminergic denervation proven by ioflupane brain scintigraphy (DaTscan®)
* DNAs from both asymptomatic parents available in biobank
* Subject affiliated to a social protection…
Contacts