Effect of Nasal Spray Dexmedetomidine on Emergence Delirium Prevention in Total Hip Replacement

Recruiting Phase 4 Interventional Study
Delirium
Prior Safety Data This treatment has already been tested in at least one earlier human trial.
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At a Glance
Age
60 and older
Sex
Any
Trial phase
Phase 4
Study type
Interventional
Purpose
Prevention
Participants needed
264 (estimated)
Sponsor
Second Affiliated Hospital, School of Medicine, Zhejiang University · Other
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About This Trial
Emergence Delirium (ED) is a common postoperative complication refers to an acute brain dysfunction that occurs during the recovery from general anesthesia, which is mainly characterized by sudden attention and consciousness disorders. The occurrence of ED increases the risk of self-injury, wound dehiscence, accidental catheter dislocation, and postoperative delirium, and is also associated with p…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: 1. Age ≥60 years old 2. Total hip arthroplasty under general anesthesia 3. ASA II-III 4. Informed consent was obtained from patients or their guardians Exclusion Criteria: 1. Allergy or contraindication to dexmedetomidine 2. Severe rhinitis and nasal deformity 3. Severe bradyc…
Contacts

Min Yan

0571-87783759

zryanmin@zju.edu.cn

CONTACT