ENavogliflozin DElivering Alleviation of Ventricular Diastolic Dysfunction in nonObstRuctive Hypertrophic CardioMyopathy

Recruiting Phase 4 Interventional Study
Nonobstructive Hypertrophic Cardiomyopathy
Prior Safety Data This treatment has already been tested in at least one earlier human trial.
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At a Glance
Age
19 – 80
Sex
Any
Trial phase
Phase 4
Study type
Interventional
Purpose
Treatment
Participants needed
200 (estimated)
Sponsor
Yonsei University · Other
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About This Trial
The primary objective of this study is to investigate the effect of enavogliflozin, an Sodium-glucose transporter 2 (SGLT2) inhibitor, compared with placebo on left ventricular diastolic function in patients with nonobstructive hypertrophic cardiomyopathy. The secondary objective of this study is to investigate the effect of enavogliflozin on exercise capacity, symptoms, serum biomarkers, and arrh…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: 1. A patient who understands the research protocol and fills out a consent form 2. Adults over 19 years of age and under 80 years of age 3. Non-diabetic or type 2 diabetic patients (HbA1c 6.5-10.5%) 4. Patients with non-obstructive hypertrophic cardiomyopathy who do not show sig…
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