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At a Glance
Age
50 – 80
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
60 (estimated)
Sponsor
Heidelberg University · Other
Who this trial is looking for
This trial is looking for people with Parkinson's disease to find out if exercise can help improve memory and thinking skills. Participants will do either cardiovascular training or stretching three times a week for twelve weeks.
Are You a Good Fit for This Trial?
You may be able to join if
I have been diagnosed with Parkinson's disease
I am between 50 and 80 years old
I can stand and walk at least 10 meters by myself
I have not done memory tasks before the study
My Parkinson's disease is at stage 3 or lower
You may not be able to join if
I have atypical Parkinsonism
I have significant cognitive impairment
I have a deep brain stimulator or brain pacemaker
I have a diagnosed psychiatric illness
I have other significant medical issues that affect exercise
I do more than the recommended amount of cardiovascular exercise
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
The study aims to assess the effects of cardiovascular (aerobic) training on memory formation and cognitive function in people with Parkinson's disease. Participants will be randomly allocated to one of two groups either performing cardiovascular training (experimental group) or stretching (control group) for twelve weeks, three times a week. The primary aim is to examine whether moderate-intense …
The study aims to assess the effects of cardiovascular (aerobic) training on memory formation and cognitive function in people with Parkinson's disease. Participants will be randomly allocated to one of two groups either performing cardiovascular training (experimental group) or stretching (control group) for twelve weeks, three times a week. The primary aim is to examine whether moderate-intense cardiovascular training (MICT) improves procedural memory formation (primary outcome) compared to stretching. Secondary outcomes include episodic memory formation, cognitive function, cardiorespiratory fitness, sleep quality, and brain-derived neurotrophic factor (BDNF) blood concentration levels.
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Eligibility Criteria
Inclusion Criteria:
* Diagnosed Parkinson's disease
* Disease stage ≤3 on the Hoehn \& Yahr scale
* Age ranging from 50 - 80 years
* Naive to the memory tasks (primary outcomes)
* Ability to stand and walk at least 10 meters independently
Exclusion Criteria:
* Atypical Parkinsonism
* Significant …
Inclusion Criteria:
* Diagnosed Parkinson's disease
* Disease stage ≤3 on the Hoehn \& Yahr scale
* Age ranging from 50 - 80 years
* Naive to the memory tasks (primary outcomes)
* Ability to stand and walk at least 10 meters independently
Exclusion Criteria:
* Atypical Parkinsonism
* Significant level of cognitive impairment (i.e., Montreal Cognitive Assessment \<21)
* Deep brain stimulation or brain pacemaker
* Diagnosed psychiatric illness
* Known clinically relevant neurological, internal or orthopedic conditions besides Parkinsonism that would interfere with the exercise paradigm
* Exceeding the recommended level of cardiovascular exercise for older adults (i.e., cardiovascular exercise done ≥150 min per week of moderate-intensity or ≥75 min per week of vigorous-intensity)
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