Early Retinal Neurodegeneration As Risk Factor, Biomarker and Pharmacological Target of Diabetic Retinopathy

Recruiting Observational Study
Diabetic Retinopathy Diabetic Retinopathy Associated with Type 2 Diabetes Mellitus
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Healthy Volunteers Welcome You do not need to have the condition being studied to take part. No Study Drug Researchers observe your health over time — no experimental treatment is given.
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At a Glance
Age
40 – 80
Sex
Any
Study type
Observational
Participants needed
180 (estimated)
Sponsor
IRCCS Ospedale San Raffaele · Other
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About This Trial
Despite the evidence that diabetic retinopathy (DR) remains the first cause of blindness among the working-age population, it lacks a specific preventive treatment. This is because early mechanisms leading to the development of DR have been, until recently, unknown. Recent studies have suggested that the early stages of DR could be preceded by neuronal abnormalities, in particular retinal ganglion…
Trial Locations
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Eligibility Criteria
Inclusion Criteria - Longitudinal study (patients): 1. Participant is willing and able to give informed consent for participation in the trial. 2. Male or Female, aged 40 - 80 years; 3. In good general health as evidenced by medical history or diagnosed with type 2 diabetes for less than 10 years w…
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