Aging, Beta Blockers, and Thermoregulatory Responses
Recruiting
Phase 4
Interventional Study
Heat Stress
Aging
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Prior Safety Data
This treatment has already been tested in at least one earlier human trial.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
At a Glance
- Age
- 65 and older
- Sex
- Any
- Trial phase
- Phase 4
- Study type
- Interventional
- Purpose
- Basic Science
- Participants needed
- 22 (estimated)
- Sponsor
- University of Texas Southwestern Medical Center · Other
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Answer a few quick questions to see if you may meet the eligibility requirements.
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About This Trial
This study will test the hypothesis that the drugs propranolol and metoprolol will result in greater increases in core body temperature during 3 hours of extreme heat exposure in older adults.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Healthy and free of any significant medical problems
* Normal resting electrocardiogram
* 65+ years of age
* Controlled cholesterol of less than 200 mg/dl
* Controlled blood pressure of less than 140/90 mmHg
Exclusion Criteria:
* Known diseases or other chronic conditions re…
Contacts