Propranolol and Metoprolol's Effects on Older Adults in Heat
Aging, Beta Blockers, and Thermoregulatory Responses
- Age
- 65 and older
- Sex
- Any
- Trial phase
- Phase 4
- Study type
- Interventional
- Purpose
- Basic Science
- Participants needed
- 22 (estimated)
- Sponsor
- University of Texas Southwestern Medical Center · Other
This trial is looking for older adults who are healthy to see how two medications, propranolol and metoprolol, affect body temperature when exposed to extreme heat for 3 hours.
You may be able to join if
- I am 65 years or older.
- I have normal cholesterol levels.
- I have controlled blood pressure.
- I am generally healthy without significant medical issues.
- I have a normal resting electrocardiogram.
You may not be able to join if
- I have a chronic condition that needs regular medical treatment.
- I have serious health problems found during routine screening.
- I smoke currently or have smoked in the last 3 years.
- I have a body mass index of 31 or more.
- I take medications that affect heart function or sweating.
Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
Check Your EligibilityThis study will test the hypothesis that the drugs propranolol and metoprolol will result in greater increases in core body temperature during 3 hours of extreme heat exposure in older adults.
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