Flow Cytometry for the Study of T-Cell Populations in Hemophagocytic Lymphohistiocytosis Associated With Lymphomas
Recruiting
Observational Study
Lymphoma
Hemophagocytic Lymphohistiocytoses
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Study type
- Observational
- Participants needed
- 150 (estimated)
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS · Other
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About This Trial
The goal of this study is to explore the associations between T cell activation and the occurrence of hemophagocytic lymphohistiocytosis (HLH) in patients with newly diagnosed lymphomas. The specific aims are:
Prediction of Lymphoma-Associated HLH (LA-HLH): Compare flow cytometric T cell activation markers with the H-score to predict LA-HLH.
Identification of new markers for predicting HLH in pa…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
1. Age \> 18 years
2. Diagnosis at onset of aggressive lymphoma including the following histotypes:
* Hodgkin lymphoma
* Transformed B cell lymphomas;
* Diffuse large B-cell lymphomas (diffuse large B-cell lymphoma NOS; T-cell/histiocyte-rich B-cell lymphoma; High grad…
Contacts