AMG 513 for Obesity Management

Single and Multiple Ascending Dose Study of AMG 513 in Participants With Obesity

Recruiting Phase 1 Interventional Study
Cardiometabolic Disease
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Healthy Volunteers Welcome You do not need to have the condition being studied to take part.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
18 – 65
Sex
Any
Trial phase
Phase 1
Study type
Interventional
Purpose
Treatment
Participants needed
80 (estimated)
Sponsor
Amgen · Industry
Who this trial is looking for

This trial is looking for adults with obesity to see how safe and well they tolerate a new treatment called AMG 513. Participants will receive either a single dose or multiple doses of the treatment during the study.

Are You a Good Fit for This Trial?

You may be able to join if

  • I am a male or female between 18 and 65 years old.
  • My body mass index (BMI) is between 30.0 and 40.0 for Part A or between 27.0 and 40.0 for Part B.
  • I am not capable of becoming pregnant.

You may not be able to join if

  • I have a history of diabetes or my blood sugar levels are too high.
  • My triglyceride levels are too high.

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

Think this trial could be right for you?

Answer a few quick questions to see if you may meet the eligibility requirements.

Check Your Eligibility
About This Trial

The primary objective of this study is to assess the safety and tolerability of AMG 513 after single and multiple doses.

Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Participants in the study will be males and females 18 to 65 years of age at the time of signing the informed consent with a body mass index (BMI) of 30.0 kg/m\^2 to 40.0 kg/m\^2 for Part A and BMI of 27.0 kg/m\^2 to 40.0 kg/m\^2 for Part B. * Females enrolled must be of non-c…
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