Endoscopic Variceal Ligation vs Carvedilol for the Prevention of First Esophageal Variceal Bleeding in Patients With HCC
Recruiting
Phase 4
Interventional Study
Hepatocellular Carcinoma (HCC)
Esophageal Varices
Prior Safety Data
This treatment has already been tested in at least one earlier human trial.
At a Glance
- Age
- 20 – 90
- Sex
- Any
- Trial phase
- Phase 4
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 120 (estimated)
- Sponsor
- Taipei Veterans General Hospital, Taiwan · Government
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About This Trial
The goal of this clinical trial is to evaluate whether endoscopic variceal ligation (EVL) or carvedilol is more effective at preventing the first esophageal variceal bleeding (EVB) in patients with hepatocellular carcinoma (HCC). It will also learn about the safety of EVL and carvedilol in patients with HCC. The main questions it aims to answer are:
Whether EVL or carvedilol is more effective at …
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
\- Patients with HCC and high-risk EVs, confirmed through imaging and clinical data (classified as F2 or F3 EVs according to Beppu et al. classification)
Exclusion Criteria:
* Age less than 20 years or greater than 90 years.
* History of esophageal variceal bleeding.
* Previou…
Contacts