Follow-up Study of Individuals with Autoantibodies Against Ro/SSA and La/SSB
Recruiting
Observational Study
Autoantibodies
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
Ready to participate?
Review the details below, then apply to join this clinical trial.
At a Glance
Age
18 and older
Sex
Any
Study type
Observational
Participants needed
500 (estimated)
Sponsor
Karolinska Institutet · Other
Who this trial is looking for
Think this trial could be right for you?
Answer a few quick questions to see if you may meet the eligibility requirements.
In this study, individuals with autoantibodies against Ro/SSA and La/SSB will be followed with regard to clinical manifestations and immunological parameters to identify immunological changes, environmental factors, and early clinical symptoms that characterize the progression from serological autoreactivity to clinically manifest disease.
Trial Locations
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Status
Eligibility Criteria
Inclusion Criteria:
To be included in the risk group, the following criteria must be met:
\- At least one instance of testing positive for Ro/SSA or La/SSB, regardless of the method used.
To be included in the control group, the individual must:
\- Have no rheumatologic disease and no autoantibo…
Inclusion Criteria:
To be included in the risk group, the following criteria must be met:
\- At least one instance of testing positive for Ro/SSA or La/SSB, regardless of the method used.
To be included in the control group, the individual must:
\- Have no rheumatologic disease and no autoantibodies against Ro/SSA or La/SSB.
Exclusion Criteria:
1. Below 18 years of age
2. Inability to consent to their own participation
3. Ongoing infection or severe illness where the study physician deems participation in the study not to be in the individuals best interest
4. Inability to read and understand Swedish, and therefore unable to complete the forms and questionnaires included in the project
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