Efficacy and Safety of Intravitreal Injection of Bevacizumab with and Without Oral Curcumin

Recruiting Phase 2 Phase 3 Interventional Study
Diabetic Macular Edema Macular Edema Retinal Neovascularization
Pivotal Trial This treatment is in the last trial phase before FDA approval. Prior Safety Data This treatment has already been tested in at least one earlier human trial.
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At a Glance
Age
40 and older
Sex
Any
Trial phase
Phase 2/3
Study type
Interventional
Purpose
Treatment
Participants needed
52 (estimated)
Sponsor
Isfahan University of Medical Sciences · Other
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About This Trial
The purpose of this study is to evaluate the effectiveness of adding curcumin oral treatment to bevacizumab intravitreal injection in patients with central macular edema. A blind study and a randomized and controlled clinical trial are conducted on diabetic patients with macular edema. The patients are divided into two intervention groups (bevacizumab + curcumin) and control (bevacizumab + placeb…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: Patients with center-involving macular edema with macular center thickness more than 300 microns in OCT 2-Patients who did not receive intravitreal bevacizumab in the last 3 months and intravitreal corticosteroids in the last 6 months. 3- The amount of BCVA should not be \<20/4…
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