Novel Therapeutic Approach for Human T-cell Malignancies

Recruiting Observational Study
T-Cell Leukemia/Lymphoma, Adult
No Study Drug Researchers observe your health over time — no experimental treatment is given.
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At a Glance
Age
18 and older
Sex
Any
Study type
Observational
Participants needed
120 (estimated)
Sponsor
Istituto Oncologico Veneto IRCCS · Other
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About This Trial
This multicenter translational study, with prospective and retrospective samples, aims to identify new strategies to selectively eliminate neoplastic T cells by modulating intracellular ROS levels. Interactions between drugs capable of activating the apoptotic process (e.g., Venetoclax) and drugs capable of altering ROS homeostasis (e.g., inhibitors of the enzyme glucose-6-phosphate dehydrogenase…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Patients with pre- and post-thymic T-cell leukemia/lymphoma * Patients of both sexes * Age of patients older than 18 years * Patient is willing to provide written and signed informed consent for participation in the study Exclusion Criteria: -Serious illness or medical condi…
Contacts

Michele Gottardi, MD

+39 0423732336

michele.gottardi@iov.veneto.it

CONTACT

GianLuca De Salvo, MD

+390498215704

gianluca.desalvo@iov.veneto.it

CONTACT