Study on the Impact of Electroacupuncture Combined With Self-Acupressure on the Quality of Life of Patients With Early-Stage Breast Cancer Undergoing Chemotherapy

Inclusion Criteria: 1. Aged 18 years or older and aged 75 years or younger, inclusive. with an Eastern Cooperative Oncology Group (ECOG) performance status of 0-2; 2. Patients who have not received prior chemotherapy and are scheduled to receive at least 4 cycles of adjuvant or neoadjuvant chemotherapy or combination targeted therapy; 3. Normal organ function with platelets ≥ 100\*10\^9/ L, hemoglobin ≥ 90 g/L, serum creatinine ≤ 1.5 mg/dl (133 mmol/L), or creatinine clearance ≥ 60 ml/min, total bilirubin ≤ 1.5 times the upper limit of normal (ULN), alanine aminotransferase ≤ 2.5 times ULN, and aspartate aminotransferase ≤ 2.5 times ULN; 4. Premenopausal women need appropriate contraception; 5. Ability to understand the study well and complete the study questionnaire. Exclusion Criteria: 1. Patients with needle phobia or allergy to stainless steel needles; and 2. Current diagnosis of mental illness (e.g., major depression, obsessive-compulsive disorder, or schizophrenia); 3. History of autoimmune diseases, blood disorders, or organ transplantation, or long-term use of hormones or immunosuppressants; 4. Comorbid bleeding disorders or thyroid dysfunction; 5. Implantation of a pacemaker; pregnancy or breastfeeding; 6. A plan for adjuvant radiotherapy in the upcoming chemotherapy cycle; 7. Current active infection; 8. Acupuncture treatment within the last four weeks; 9. Patients who are allergic to the drugs used; 10. Use of other Traditional Chinese Medicine (TCM) techniques such as Chinese herbs in the next chemotherapy cycle.