Tumor-Informed ctDNA Testing for MRD Following Treatment of Squamous Cell Carcinoma
Recruiting
Observational Study
Squamous Cell Carcinoma of Head and NeckSquamous Cell Carcinoma Head and Neck Cancer (HNSCC)Squamous Cell Carcinoma of SkinCutaneous Squamous Cell Carcinoma (CSCC)
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
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At a Glance
Age
18 and older
Sex
Any
Study type
Observational
Participants needed
250 (estimated)
Sponsor
University of California, San Francisco · Other
Who this trial is looking for
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This is a single-center, non-interventional, observational study that evaluates the correlation of circulating tumor DNA (ctDNA) testing to cancer relapse for participants with squamous cell carcinomas (HNC) of the head and neck mucosa and skin after curative-intent primary radiation or surgery.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
1. Participants must have histologically or cytologically confirmed squamous cell carcinoma of the head and neck mucosa and skin.
2. Participants must be age \>=18 years.
3. Participants must be planning to receive curative-intent surgery or radiation-based treatment as part of …
Inclusion Criteria:
1. Participants must have histologically or cytologically confirmed squamous cell carcinoma of the head and neck mucosa and skin.
2. Participants must be age \>=18 years.
3. Participants must be planning to receive curative-intent surgery or radiation-based treatment as part of standard of care treatment.
4. Participants must have the ability to understand and the willingness to sign a written informed consent document.
Exclusion Criteria:
1\. Contraindication to phlebotomy for removal of 20 mL of peripheral blood each time point (up to 300 mL total over 15 time points).
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